Sigma-LIGAND-1 hydrochloride (C007B-417851)

Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC 50 s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a K i of 4000 nM at the dopamine D 2 receptorIn VivoAdministration of Sigma-LIGAND-1 hydrochloride reverseS amphetamine-induced hyperlocomotion in mice, a behavioral model sensitive to antipsychotic compounds. Sigma-LIGAND-1 hydrochloride and its structural analogues have the potential antipsychotic activity . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 16 nM (DTG site of sigma receptor), 19 nM (PPP site of sigma receptor), Ki: 4000 nM (Dopamine D2 receptor).

Specifications and Purity: ≥99%

Molecular Formula: C27H34ClNO4

Molecular Weight: 472.02

PubChem CID: 9890958

Isomeric SMILES: CC1=C(OC2=C(C1=O)C=C(C=C2)OCCCCCCN3CCC(CC3)O)C4=CC=CC=C4.Cl