Sigma-LIGAND-1 is a selective sigma receptor ligand with an IC 50 s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a K i of 4000 nM at the dopamine D 2 receptorIn VivoAdministration of Sigma-LIGAND-1 would reverse amphetamine-induced hyperlocomotion in mice, a behavioral model sensitive to antipsychotic compounds. Sigma-LIGAND-1 and its structural analogues have the potential antipsychotic activity . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 16 nM (DTG site of sigma receptor), 19 nM (PPP site of sigma receptor), Ki: 4000 nM (Dopamine D2 receptor).
Specifications and Purity: ≥99%
Molecular Formula: C27H33NO4
Molecular Weight: 435.56
- UPC:
- 12141731
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S648620-5mg
- CAS:
- 139652-01-0
- Product Size:
- 5mg
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