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Nutlin-3

Catalog No.
C008B-273873
Manufacturer No.
N126055-5mg
Manufacturer Name
ALADDIN SCIENTIFIC
Quantity
1
Unit of Measure
EA

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Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM; stabilizes p73 in p53-deficient cells.Disrupts MDM2-p53 interaction, inducing apoptosis.

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Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM; stabilizes p73 in p53-deficient cells.Disrupts MDM2-p53 interaction, inducing apoptosis.


Potent, selective MDM2 antagonist


Specifications & Purity: Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM; stabilizes p73 in p53-deficient cells.Disrupts MDM2-p53 interaction, inducing apoptosis.


MDL Number: MFCD07784509


Molecular Formula: C30H30Cl2N4O4


Molecular Weight: 581.49


EC Number: 637-233-8


PubChem CID: 216345


Isomeric SMILES: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl


Storage Temperature: Store at -20°C


Shipped in: Ice chest + Ice pads


More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/N126055-SCI_722ef414ee45334195afad9bcf547f52.pdf


UPC:
51142509
HazmatClass:
Yes
WeightUOM:
LB
MPN:
N126055-5mg
Country of Origin:
China
CAS:
548472-68-0
Product Size:
5mg
Harmonized Tariff Code:
2931.90.90
Hazard Statement Codes:
H315;H319;H335
Precautionary Statement Codes:
P261;P264;P271;P280;P321;P302+P352;P304+P340;P305+P351+P338;P362+P364;P405;P403+P233;P501;P264+P265;P337+P317;P332+P317;P319

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