Nutlin-3 (C007B-237758)

Catalog No.: C007B-237758
Manufacturer No.: N126055-10mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM: stabilizes p73 in p53-deficient cells.Disrupts MDM2-p53 interaction, inducing apoptosis.

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Description
Specifications

Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM; stabilizes p73 in p53-deficient cells.Disrupts MDM2-p53 interaction, inducing apoptosis.

Specifications and Purity: ≥98%

MDL Number: MFCD07784509

Molecular Formula: C30H30Cl2N4O4

Molecular Weight: 581.49

PubChem CID: 216345

Isomeric SMILES: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/N126055-SCI_722ef414ee45334195afad9bcf547f52.pdf

UPC:: 51142509
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: N126055-10mg
CAS:: 548472-68-0
Product Size:: 10mg
Hazard Statement Codes:: H335:H319:H315
Precautionary Statement Codes:: P501:P403+P233:P405:P362+P364:P305+P351+P338:P304+P340:P302+P352:P280:P271:P264:P261

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