MANUMYCIN A FROM STREPTOMYCES PARVULUS

Catalog No.: C005B-453727
Manufacturer No.: M6418-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Application Manumycin A from Streptomyces parvulus has been used to inhibit Iκ:B kinase (IKK)b−:nuclear κ:-B essential modulator (NEMO) interaction in the homogeneous time-resolved fluorescence (HTRF)-based binding assay.

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Description
Specifications

Application

Manumycin A from Streptomyces parvulus has been used to inhibit IκB kinase (IKK)b−nuclear κ-B essential modulator (NEMO) interaction in the homogeneous time-resolved fluorescence (HTRF)-based binding assay.

Biochem/physiol Actions

Manumycin A is a natural monomeric epoxyquinoid. It has an ability to inhibit tumor necrosis factor (TNF) induced IκB kinase (IKK) activity in various cell types. In addition, manumycin A exhibits anti-tumor property by inhibiting farnesylation of oncogenic Ras.

Potent inhibitor of Ras farnesyltransferase.

UPC:: 51111704
Condition:: New
HazmatClass:: No
MPN:: M6418-5MG
CAS:: 52665-74-4

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