BORRELIDIN FROM STREPTOMYCES PARVULUS

General description

Chemical structure: macrolide

Biochem/physiol Actions

Borrelidin is a potent angiogenesis inhibitor that induces apoptosis in capillary tube-forming cells. Also displays antimalarial activity against drug-resistant Plasmodia. Antimicrobial and selective threonyl t-RNA synthetase inhibitor.

Molecular Weight: 489.64. Empirical Formula: C₂₈H₄₃NO₆. biological source: Streptomyces parvulus. Quality Level: 200. Assay: ≥. 98% (HPLC). form: powder. solubility: DMSO: 1 . mg/mL, methanol: 1 . mg/mL. antibiotic activity spectrum: viruses. Mode of action: enzyme | inhibits. shipped in: wet ice. storage temp.: −. 20°C. SMILES string: [H][C@]1(CCC[C@H]1C(O): O)[C@@H]2C\C: C\C: C(C#N)[C@H](O)[C@@H](C)C[C@H](C)C[C@H](C)C[C@H](C)[C@@H](O)CC(: O)O2. InChI: 1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1. InChI key: OJCKRNPLOZHAOU-UGKRXNSESA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).