Biochem/physiol Actions
Interleukin-13 is a pleiotropic cytokine produced by activated Th2 cells in the mouse and human. IL-13 is secreted mainly as an unglycosylated protein of 132 amino acids with a molecular weight of 10,000 daltons. A 4.3kb DNA fragment of the mouse IL-13 gene was sequenced and occurs as a single copy mapping a chromosome 11. In the human, a 4.6 kb DNA segment of the IL-13 gene occurs as a single copy and maps to chromosome 5. IL-13 induces B cell proliferation and also induces IgE switching. The proliferative activity of human and mouse IL-13 products are tested in culture using the human erythroleukemic cell line TF-1.
Physical form
lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (PBS), pH 7.4, with 50 μg bovine serum albumin (BSA) per 1 μg of cytokine
biological source: mouse. Quality Level: 100. recombinant: expressed in E. coli. Assay: ≥. 97% (SDS-PAGE). form: lyophilized powder. potency: 1-10 . ng/mL EC50. mol wt: 11.5 . kDa (predicted. 9 kDa under reducing conditions). packaging: pkg of 5 . μ. g. technique(s): cell culture | mammalian: suitable. impurities: endotoxin, tested. UniProt accession no.: P20109. storage temp.: −. 20°C. Gene Information: mouse ... Il13(16163). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.- UPC:
- 10101510
- Condition:
- New
- HazmatClass:
- No
- MPN:
- I1896-5UG
akash.verma@cenmed.com
(732) 447-1115





