Biochem/physiol Actions
Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.
Unit Definition
One unit will reduce 1 nanomole of cytochrome C per minute at pH 7.4 at 37 deg C.
Physical form
Solution in 100 mM potassium phosphate buffer, pH 7.4.
Preparation Note
Microsomes containing human CYP1B1 and recombinant human NADPH-P450 reductase.
Analysis Note
Tested for the ability to catalyze the 7-deethylation of ethoxyresorufin.
biological source: human. Quality Level: 200. recombinant: expressed in baculovirus infected insect cells (BTI-TN-5B1-4). form: solution. mol wt: 45-60 . kDa. packaging: vial of 0.5 . nmol. UniProt accession no.: Q16678. application(s): cell analysis. shipped in: dry ice. storage temp.: −. 70°C. Gene Information: human ... CYP1B1(1545). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51182008
- Condition:
- New
- HazmatClass:
- No
- MPN:
- C3860-1VL
- Temperature Control Device:
- Yes
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