Biochem/physiol Actions
Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.
Other Notes
Microsomes containing recombinant human CYP3A4 and recombinant rabbit NADPH-P450 reductase
Unit Definition
One unit will convert 1 nanomole of testosterone to 6β-hydroxytestosterone per minute at pH 7.4 at 37 °C.
Physical form
Solution in 100 mM potassium phosphate buffer, pH 7.4.
biological source: human. Quality Level: 200. recombinant: expressed in baculovirus infected insect cells (BTI-TN-5B1-4). form: solution. mol wt: 45-60 . kDa. packaging: vial of ~0.5 . nmol, vial of ≥. 25 . units. UniProt accession no.: P08684. application(s): cell analysis. shipped in: dry ice. storage temp.: −. 70°C. Gene Information: human ... CYP3A4(1576). Storage Class Code: 10 - Combustible liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51182008
- Condition:
- New
- HazmatClass:
- No
- MPN:
- C4982-1VL
- Temperature Control Device:
- Yes
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