COCAINE FREE BASE--DEA SCHEDULE II ITEM

Biochem/physiol Actions

Inhibits the dopamine, norepinephrine, and serotonin transporters with K_is of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

Molecular Weight: 303.35. Empirical Formula: C₁₇H₂₁NO₄. form: powder. Quality Level: 200. drug control: USDEA Schedule II. Home Office Schedule 2. stupéfiant (France). kontrollierte Droge in Deutschland. regulated under CDSA - not available from Sigma-Aldrich Canada. estupefaciente (Spain). Decreto Lei 15/93: Tabela IB (Portugal). application(s): forensics and toxicology. SMILES string: [H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(: O)c3ccccc3)C(: O)OC)N2C. InChI: 1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1. InChI key: ZPUCINDJVBIVPJ-LJISPDSOSA-N. Gene Information: human ... DRD3(1814), KCNH1(3756), KCNH2(3757), SCN10A(6336), SCN11A(11280), SCN5A(6331), SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)
mouse ... Slc6a2(20538)
rat ... Chrm1(25229), Slc6a3(24898), Slc6a4(25553). Pictograms: GHS06,GHS08. Signal Word: Danger. Hazard Statements: H300 + H330 - H336 - H361d. Precautionary Statements: P202 - P260 - P264 - P271 - P280 - P304 + P340 + P310. Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3. Target Organs: Central nervous system. Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges.