BOC-HIS(TRT)-OH 25 G

General description

A protected histidine derivative for only the critical coupling step in Boc SPPS. After coupling the Boc- and Trt-groups are cleaved simultaneously by TFA.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Linkage

Replaces: 04-12-0160

Analysis Note

Colour (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 4.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 497.58. Empirical Formula: C₃₀H₃₁N₃O₄. Quality Level: 200. product line: Novabiochem^®. . Assay: ≥. 95.0% (acidimetric), ≥. 98% (TLC), ≥. 98.0% (HPLC). form: powder. reaction suitability: reaction type: Boc solid-phase peptide synthesis. manufacturer/tradename: Novabiochem^®. . mp: 130 . °C (decomposition). application(s): peptide synthesis. storage temp.: 15-25°C. InChI: 1S/C30H31N3O4/c1-29(2,3)37-28(36)32-26(27(34)35)19-25-20-33(21-31-25)30(22-13-7-4-8-14-22,23-15-9-5-10-16-23)24-17-11-6-12-18-24/h4-18,20-21,26H,19H2,1-3H3,(H,32,36)(H,34,35)/t26-/m0/s1. InChI key: OYXZPXVCRAAKCM-SANMLTNESA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.