Name: N-CBZ-VAL-ALA-ASP FLUOROMETHYL KETONE
SKU: C005B-020771
Availability: OutOfStock

N-CBZ-VAL-ALA-ASP FLUOROMETHYL KETONE

Catalog No.

C005B-020771

Manufacturer No.

C2105-3MG

Manufacturer Name

Sigma-Aldrich

Quantity

Unit of Measure

Amino Acid Sequence Z-Val-Ala-Asp-OMe-FMK Biochem/physiol Actions Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to

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Description
Specifications

Amino Acid Sequence

Z-Val-Ala-Asp-OMe-FMK

Biochem/physiol Actions

Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Molecular Weight: 453.46. Empirical Formula: C₂₁H₂₈FN₃O₇. Quality Level: 200. Assay: ≥. 90% (TLC). form: powder. shipped in: dry ice. storage temp.: −. 20Â°C. SMILES string: CC(C)[C@H](NC(: O)OCc1ccccc1)C(: O)N[C@@H](C)C(: O)N[C@@H](CC(O): O)C(: O)CF. InChI: 1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1. InChI key: SUUHZYLYARUNIA-YEWWUXTCSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).