N-CBZ-GLY-PRO-ARG P-NITROANILIDE ACETATE

Application

Z-Gly-Pro-Arg p-nitroanilide acetate salt has been used as a substrate in prostate-specific antigen (PSA) activation protease assay for determining enterokinase-PSA-trypsin (EK-PSA-TRP) activity and to perform kinetic experiments. It has also been used as a substrate to measure the pancreatic trypsin activity chromogenically.

Molecular Weight: 582.61 (free base basis). Empirical Formula: C₂₇H₃₄N₈O₇ · xC₂H₄O₂. Quality Level: 200. Assay: ≥. 98% (TLC). form: powder. solubility: methanol: 20 . mg/mL, clear, colorless to light yellow. storage temp.: −. 20°C. SMILES string: CC(O): O.NC(: N)NCCC[C@H](NC(: O)[C@@H]1CCCN1C(: O)CNC(: O)OCc2ccccc2)C(: O)Nc3ccc(cc3)[N+]([O-]): O. InChI: 1S/C27H34N8O7.C2H4O2/c28-26(29)30-14-4-8-21(24(37)32-19-10-12-20(13-11-19)35(40)41)33-25(38)22-9-5-15-34(22)23(36)16-31-27(39)42-17-18-6-2-1-3-7-18. 1-2(3)4/h1-3,6-7,10-13,21-22H,4-5,8-9,14-17H2,(H,31,39)(H,32,37)(H,33,38)(H4,28,29,30). 1H3,(H,3,4)/t21-,22-. /m0./s1. InChI key: FPMAXHHYPVIJMC-VROPFNGYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).