YM-26734 (C005B-312389)

Catalog No.: C005B-312389
Manufacturer No.: SML1226-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Biochem/physiol Actions YM-26734 is a competitive inhibitor of the secreted (Group II) form of phospholipase A2. The IC 50 against rabbit platelet derived sPLA2 is 85 nM.

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Description
Specifications

Biochem/physiol Actions

YM-26734 is a competitive inhibitor of the secreted (Group II) form of phospholipase A2. The IC₅₀against rabbit platelet derived sPLA2 is 85 nM. YM-26734 is active against, but less potent for group I (pancreatic) sPLA2 (porcine pancreatic enzyme IC₅₀ = 7 μM), and does not inhibit intracellular PLA2 isoforms.

YM-26734 is a natural product analog and a derivative of YM-26567-1, which is found in the fruit of Horsfieldia amygdaline. It exhibits a broad inhibitory spectrum towards different sPLA2s.

UPC:: 41105601
Condition:: New
HazmatClass:: No
MPN:: SML1226-25MG
CAS:: 144337-18-8

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