A kaempferol glycoside that selectively inhibits RSK2 with an IC50 value of 89 nM (Ki = 1 &muM) without interfering with upstream activators of RSK, including ERK, MEK, EGFR, and PKC inhibits the proliferation of MCF-7 breast cancer cells at 100
A kaempferol glycoside that selectively inhibits RSK2 with an IC50 value of 89 nM (Ki = 1 &muM) without interfering with upstream activators of RSK, including ERK, MEK, EGFR, and PKC inhibits the proliferation of MCF-7 breast cancer cells at 100
Aldehyde dehydrogenases (ALDHs) represent a group of enzymes that oxidize a wide range of endogenous and exogenous aldehydes to their corresponding carboxylic acids, which affect both developmental and toxicological functions. Pharmacological
Aldehyde dehydrogenases (ALDHs) represent a group of enzymes that oxidize a wide range of endogenous and exogenous aldehydes to their corresponding carboxylic acids, which affect both developmental and toxicological functions. Pharmacological
A potent antagonist of the LTB4 receptor, BLT1, that inhibits the specific binding of radiolabeled LTB4 to isolated human neutrophils (IC50 value of 17.6 nM) inhibits the LTB4-induced chemotaxis of human neutrophils (IC50 value of 6.3 nM).
A potent antagonist of the LTB4 receptor, BLT1, that inhibits the specific binding of radiolabeled LTB4 to isolated human neutrophils (IC50 value of 17.6 nM) inhibits the LTB4-induced chemotaxis of human neutrophils (IC50 value of 6.3 nM).
For quantitative determination of pyruvate and evaluation of drug effects on its metabolism. Linear detection range 2 - 500 &muM pyruvate for colorimetric assays and 0.
For quantitative determination of pyruvate and evaluation of drug effects on its metabolism. Linear detection range 2 - 500 &muM pyruvate for colorimetric assays and 0.