Biochem/physiol Actions
STF-1084 (ENPP1 inhibitor Compound 15) Is a cell-impermeable, potent, selective, stable and nontoxic competitive inhibitor of ENPP1 (ectonucleotide pyrophosphatase phosphodiesterase 1) that inhibit degradation of extracellular cGAMP under physiological conditions. STF-1084 had no effect on intracellular cGAMP. STF-1084 synergized with IR to significantly delay tumor progression in three triple-negative breast cancer cell lines 4T1-luc mice model.
- UPC:
- 42201805
- Condition:
- New
- HazmatClass:
- No
- MPN:
- SML3553-25MG
- CAS:
- 2298390-71-1
akash.verma@cenmed.com
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