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(r)-cpp (c15-1619-124)

(R)-CPP (C005B-474440)

Catalog No.
C005B-474440
Manufacturer No.
5048390001
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
EA

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General description A highly potent antagonist slightly selective for NR2A over other subtype NMDA receptors (K i = 0.041, 0.

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General description

A highly potent antagonist slightly selective for NR2A over other subtype NMDA receptors (Ki = 0.041, 0.27, 0.63 and 1.99 µM for NMDA subtypes NR2A, NR2B, NR2C, and NR2D, respectively). Commonly used for various research in brain functions and disorders that neurotransmissions via NMDA receptors are involved.

Biochem/physiol Actions

Primary Target
NMDA receptors

Target Ki: 0.041, 0.27, 0.63 and 1.99 →M for NMDA subtypes NR2A, NR2B, NR2C, and NR2D, respectively.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Murphy, R., et al. 2012. Psychopharmacol.219, 401.
Paoletti, P., et al. 2007. Curr. Opin. Pharmacol.7, 47.
Feng, B., et al. 2004. Br. J. Pharmacol.141, 508.
Lowe, A., et al. 1990. Neurosci. Lett.113, 315.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

UPC:
42192201
Condition:
New
HazmatClass:
No
MPN:
5048390001
CAS:
126453-07-4

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