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(+/-)-cpp (c15-1199-562)

(+/-)-CPP (C005B-003747)

Catalog No.
C005B-003747
Manufacturer No.
C104-100MG
Manufacturer Name
Sigma-Aldrich
Quantity
100
Unit of Measure
MG

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Application (±)-CPP has been used as an uncompetitive NMDA receptor antagonist: to study its effects on blood glucose in mice in electrophysiological recording in mouse brain slices in electrophysiological recording in rat hippocampal pyramid

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Application

(±)-CPP has been used as an uncompetitive NMDA receptor antagonist:

  • to study its effects on blood glucose in mice
  • in electrophysiological recording in mouse brain slices
  • in electrophysiological recording in rat hippocampal pyramidal neurons

Biochem/physiol Actions

3-(2-carboxypiperazin-4yl) propyl-1-phosphonic acid (CPP) is a potent, competitive, and selective N-methyl-D-aspartate (NMDA) receptor antagonist. It is an analog of 2-amino-7-phosphonoheptanoic acid. CPP shows anticonvulusant and antinociceptive activity.

Caution

Hygroscopic

Molecular Weight: 252.20. Empirical Formula: C8H17N2O5P. form: solid. Quality Level: 100. color: white. solubility: H2O: 99.2 . mg/mL, ethanol: insoluble. SMILES string: OC(: O)C1CN(CCCP(O)(O): O)CCN1. InChI: 1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15). InChI key: CUVGUPIVTLGRGI-UHFFFAOYSA-N. Gene Information: human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)
rat ... Grin2a(24409). Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.
UPC:
51111707
Condition:
New
HazmatClass:
No
MPN:
C104-100MG
CAS:
100828-16-8

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