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pseudomonas exotoxin a from pseudomonas aeruginosa

PSEUDOMONAS EXOTOXIN A FROM PSEUDOMONAS AERUGINOSA

Catalog No.
C005B-440858
Manufacturer No.
P0184-.5MG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
MG

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General description Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa. It is a member of the family mono-ADP-ribosyltransferases.

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General description

Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa. It is a member of the family mono-ADP-ribosyltransferases.

Biochem/physiol Actions

Pseudomonas exotoxin A functions as an anticancer agent.
It catalyses the transfer of ADP-ribose moiety of NAD+ to the histidine imidazole ring of diphthamide.
Shown to be toxic to animals and to cell lines, and to inhibit protein synthesis via ADP ribosylation of elongation factor 2.

Packaging

Package size based on protein content.

Physical form

Lyophilized powder containing Tris buffer, EDTA, NaCl and lactose

UPC:
51101513
Condition:
New
HazmatClass:
Yes
MPN:
P0184-.5MG
CAS:
91262-95-2

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