PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC50 of 115 nM. PD-L1-IN-1 strongly binds with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells enhanced antitumor immune activity of the latter. PD-L1-IN-1 significantly increased interferon γ release and apoptotic induction of cancer cells, with low cytotoxicity in healthy cells.
Specifications and Purity: average Mw >15,000,powder (Infusible),3-100μm particle size
MDL Number: MFCD00284320
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/P478292-SCI_1dbea9ce81c375d83c9c8427e96c2836.pdf
- UPC:
- 12171604
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- P478292-5g
- CAS:
- 2767424-13-3
- Product Size:
- 5g
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