PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) with an IC 50 of 0.28 μM; also inhibits 5-lipoxygenase with an IC 50 of 1.05 μM.In VitroThe synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans ). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC 50 =0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC 50 =1.05 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:5-Lipoxygenase 1.05 μM (IC 50 ).
Specifications and Purity: ≥99%
Molecular Formula: C19H26O3
Molecular Weight: 302.41
- UPC:
- 85101509
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- P649115-5mg
- CAS:
- 102271-49-8
- Product Size:
- 5mg
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