PG 01 (C007B-409705)

Catalog No.: C007B-409705
Manufacturer No.: P286576-10mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

Product description：PG01 is a potent CFTR Cl- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>:E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively. PG01 is also

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Description
Specifications

Product description：PG01 is a potent CFTR Cl- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively. PG01 is also effective on ΔF508 (Ka of 0.3 μM). PG01 increases ΔF508-CFTR Cl- current after adding Forskolin。.

Specifications and Purity: ≥98%(HPLC)

Molecular Formula: C₂₈H₂₉N₃O₂

Molecular Weight: 439.55

PubChem CID: 4695397

Isomeric SMILES: CC(C)C1=CC=C(C=C1)NC(=O)C(C2=CC=CC=C2)N(C)C(=O)CC3=CNC4=CC=CC=C43

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/P286576-SCI_6844e5bebc3664449792686446594de2.pdf

UPC:: 85131709
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: P286576-10mg
CAS:: 853138-65-5
Product Size:: 10mg
Hazard Statement Codes:: H413:H302
Precautionary Statement Codes:: P501:P301+P312:P330:P273:P270:P264

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