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Neratinib (HKI-272) (C007B-392580)

Catalog No.
C007B-392580
Manufacturer No.
N425586-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM: weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3.A potent and selective inhibitor of

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Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM; weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3.A potent and selective inhibitor of EGFR and HER2.

Specifications and Purity: 2mM in DMSO

Molecular Formula: C30H29ClN6O3

Molecular Weight: 557.04

PubChem CID: 9915743

Isomeric SMILES: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C

UPC:
41115812
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
N425586-1ml
CAS:
698387-09-6
Product Size:
1ml

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