Neratinib-d6 (C007B-378443)

Catalog No.: C007B-378443
Manufacturer No.: N647202-5mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

Neratinib-d 6 (HKI-272-d6) is the deuterium labeled Neratinib. Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC50s of 59 nM and 92 nM for HER2 and EGFR , respectively.In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Formula: C30H23D6ClN6O3

Molecular Weight: 563.08

PubChem CID: 49870271

Isomeric SMILES: [2H]C([2H])([2H])N(C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)OCC)C([2H])([2H])[2H]

UPC:: 51152008
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: N647202-5mg
CAS:: 1259519-18-0
Product Size:: 5mg

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