Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM; weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3.A potent and selective inhibitor of EGFR and HER2
Specification: Moligand™, ≥99%
Molecular Formula: C30H29ClN6O3
Molecular Weight: 557.04
PubChem CID: 9915743
Isomeric SMILES: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/N126132-SCI_6fb8127f4c764ca6a4d676037eb9b660.pdf
- UPC:
- 12141728
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N126132-1g
- Product Size:
- 1g
- CAS:
- 698387-09-6
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