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MSBT-ALKYNE

Catalog No.
C005B-027963
Manufacturer No.
927619-50MG
Manufacturer Name
Sigma-Aldrich
Quantity
50
Unit of Measure
MG

Application MSBT-alkyne is a probe that can be used to label cysteines through nucleophilic aromatic substitution. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in

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Application

MSBT-alkyne is a probe that can be used to label cysteines through nucleophilic aromatic substitution. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitative applications (Zanon et al. 2021). The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis (Zanon et al. 2020). Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow (Weerapana et al. 2010, Backus et al. 2016).

Molecular Weight: 294.35. Empirical Formula: C12H10N2O3S2. Quality Level: 100. Assay: ≥. 95%. form: powder. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
12352003
Condition:
New
HazmatClass:
No
MPN:
927619-50MG
CAS:
2550394-04-0

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