ML390 (C007B-231477)

Catalog No.: C007B-231477
Manufacturer No.: M422468-1ml
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationML390 ML390 is a human DHODH inhibitor with an IC50 of 0.56 μM and induces differentiation in acute myeloid leukemia.TargetsDHODH (Cell-free assay) 0.56 μMIn vitroML390 was active with an ED50 (effective concentration triggering 50% of its maximal differentiation activity) of 2 μM in murine and human AML cell lines, offering insight into the mechanism of overcoming differentiation arrest. DHODH inhibitors demonstrated effective at prolonging survival in animal models of leukemia.Cell Research(from reference)Cell lines：Lys-GFP-ER-HoxA9 cells Concentrations：10 μM Incubation Time：48 h.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C21H21F3N2O3

Molecular Weight: 406.4

PubChem CID: 71768304

Isomeric SMILES: C1C[C@H](C2=CC=CC=C2C1)NC(=O)CCNC(=O)C3=CC=C(C=C3)OC(F)(F)F

UPC:: 41104301
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: M422468-1ml
CAS:: 2029049-79-2
Product Size:: 1ml

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