ML291

Catalog No.: C005B-312705
Manufacturer No.: SML0978-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Biochem/physiol Actions ML291 specifically activates the apoptotic arm of the cellular unfolded protein response ( UPR) EC 50 = 762 nM) with 105-fold selectivity over activation of the adaptive UPR pathway. ML291 induces apoptosis in wild-type

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Description
Specifications

Biochem/physiol Actions

ML291 specifically activates the apoptotic arm of the cellular unfolded protein response ( UPR) EC₅₀ = 762 nM) with 105-fold selectivity over activation of the adaptive UPR pathway. ML291 induces apoptosis in wild-type mouse embryonic fibroblasts (MEFs), but not in CHOP KO MEFs.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

UPC:: 41105601
Condition:: New
HazmatClass:: No
MPN:: SML0978-5MG
CAS:: 1523437-16-2

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