MITOXANTRONE DIHYDROCHLORIDE (C005B-453706)

Catalog No.: C005B-453706
Manufacturer No.: M6545-50MG
Manufacturer Name: Sigma-Aldrich
Quantity: 50
Unit of Measure: MG

Application Mitoxantrone dihydrochloride has been used: to induce calreticulin surface expression in cells as a genotoxin agent as a topoisomerase inhibitor Biochem/physiol Actions Mitoxantrone is a cytostatic anthracenedione that

Enjoy exclusive benefits including discounted pricing on orders by contacting our Sales Executives to open an account. Contact Us

Description
Specifications

Application

Mitoxantrone dihydrochloride has been used:

to induce calreticulin surface expression in cells
as a genotoxin agent
as a topoisomerase inhibitor

Biochem/physiol Actions

Mitoxantrone is a cytostatic anthracenedione that intercalates in DNA and increases the incidence of double-strand breaks by stabilizing the cleavable complex of topoisomerase II and DNA. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells. It used clinically as a chemotherapeutic agent against leukemias and solid tumors and as an immune system modulator in multiple sclerosis.

UPC:: 51111603
Condition:: New
HazmatClass:: No
MPN:: M6545-50MG
CAS:: 70476-82-3

Cenmed Satisfaction Guarantee

At Cenmed, your confidence and satisfaction are paramount. We guarantee the quality and reliability of our extensive range of clinical and laboratory supplies. If you're not completely satisfied with your purchase, we offer a straightforward return process and dedicated support to resolve your concerns promptly. Our commitment ensures that you can order with confidence, knowing that Cenmed is dedicated to superior service and customer satisfaction. Trust us to meet your needs with every order, backed by our promise of excellence. Learn more in Help & FAQs.

"Cenmed provides me access to the same products/services normally reserved for much larger labs than mine. I was presently surprised by their product offering."