Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic cytostatic anthraquinone derivative. Induces DNA damage by intercalating into DNA and inhibiting Topo II (topoisomerase II). Mitoxantrone dihydrochloride induces interstrand DNA cross-links and DNA-protein cross-links in cellular systems. Mitoxantrone dihydrochloride has recently been shown to be an inhibitor of DNA methylation.Induces DNA damage by intercalating into DNA and inhibiting Topo II;It can be used to induce calreticulin surface expression in cells, as a genotoxin agent,as a topoisomerase inhibitor.
Specifications and Purity: ≥97%
MDL Number: MFCD00242943
Molecular Formula: C22H28N4O6·2HCl
Molecular Weight: 517.4
PubChem CID: 51082
Isomeric SMILES: C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/M129460-SCI_2d2f3dbf85343f30645847d75925fa80.pdf
- UPC:
- 51111603
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M129460-50mg
- CAS:
- 70476-82-3
- Product Size:
- 50mg
- Hazard Statement Codes:
- H360:H340:H302
- Precautionary Statement Codes:
- P501:P405:P308+P313:P301+P312:P281:P280
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