InformationLuteolin (Luteoline, Luteolol, Digitoflavone) is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively. Phase 2.In vitroLuteolin is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively. Luteolin inhibits LPS-stimulated TNF-alpha production with an IC50 of less than 1 μM. Luteolin inhibites LPS-induced phosphorylation of Akt as well as IkappaBalpha.In vivoLD50: Mice >2500mg/kg (i.g.)Cell Datacell lines:Concentrations:Incubation Time:Powder Purity:≥97%.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C15H10O6
Molecular Weight: 286.24
- UPC:
- 51321705
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L409168-1ml
- CAS:
- 491-70-3
- Product Size:
- 1ml
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