Luteolin is an antioxidant flavonoid and a free radical scavenger. It inhibits rat liver cytosolic glutathione S-transferase activity and soybean and reticulocyte 15-LO (15-lipoxygenases). Luteolin also shows cytotoxic effects on Raji lymphoma cells. Incubation of the non-tumor cell line C3H10T?CL8 with luteolin results in induction of p53 accumulation and apoptosis, with apoptosis occurring at the G2/M phase of the cell cycle. Luteolin is an inhibitor of Cot, PDE1-5, c-Src, HDAC, Maltase-glucoamylase, Topo I, PKC ε, Fatty Acid Synthase, PPAR γ and MMP.An inhibitor of glutathione S-transferase and 15-LO.
Specifications and Purity: ≥98%(HPLC)
MDL Number: MFCD00017309
Molecular Formula: C15H10O6
Molecular Weight: 286.24
EC Number: 207-741-0
PubChem CID: 5280445
Isomeric SMILES: C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O
Beilstein Registry Number: 292084
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/L107329-SCI_c2f4541508839b5e1697328f02a6fc00.pdf
- UPC:
- 51321705
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L107329-1g
- CAS:
- 491-70-3
- Product Size:
- 1g
- Hazard Statement Codes:
- H335:H319:H315
- Precautionary Statement Codes:
- P501:P403+P233:P405:P362+P364:P305+P351+P338:P304+P340:P302+P352:P280:P271:P264:P261
akash.verma@cenmed.com
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