Lotilaner is a parasiticide , acts as a potent non-competitive antagonist of insects GABACl receptors , with an IC 50 of 23.84 nM for Drosophila melanogaster GABA receptor . No effect on a dog GABAA receptorIn VitroLotilaner shows IC 50 s of 38.25 ± 3.75, 52.40 ± 4.54, 36.79 ± 4.39 nM for Drosophila melanogaster dieldrin/fipronil-resistant forms (DmR2), Lepeophtheirus salmonis (Ls) and Rhipicephalus microplus (Rm) GABACl receptors, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:IC50: 23.84 nM (DmS-GABA), 38.25 nM (DmR2-GABA), 52.40 nM (Ls-GABA1), 36.79 nM (Rm-GABA).
Specifications and Purity: 10mM in DMSO
Molecular Formula: C20H14Cl3F6N3O3S
Molecular Weight: 596.76
- UPC:
- 41103813
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L656491-1ml
- CAS:
- 1369852-71-0
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





