Lck inhibitor 2 (C007B-364612)

Catalog No.: C007B-364612
Manufacturer No.: L648683-5mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK , LYN, SYK , and TXK. The IC50 values are 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk , Lyn, Btk and Txk respectivelyIC50 Value: 13 nM(Lck) Target: Src family kinaseLck inhibitor 2(Compound 9) inhibited 48 kinases with %control < 1 (33 of them tyrosine kinases, almost half of the 71 tyrosine kinases in the panel). A further 27 kinases were bound with %control < 10. Kd values for 16 kinases were determined and found to be below 100 nM. These included TXK (10 nM).Form:Solid.

Specifications and Purity: ≥99%

Molecular Formula: C18H17N5O2

Molecular Weight: 335.36

PubChem CID: 25138012

Isomeric SMILES: CC1=C(C=C(C=C1)O)NC2=NC(=NC=C2)NC3=CC=CC(=C3)C(=O)N

UPC:: 51111602
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: L648683-5mg
CAS:: 944795-06-6
Product Size:: 5mg

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