Alpha beta counters

306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).Form:Liquid.

306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).Form:Liquid.

M1002 is a hypoxia-inducible factor-2 ( HIF-2 ) agonist, and can enhance the expression of HIF-2 target genes. M1002 shows synergy with prolyl-hydroxylase domain (PHD) inhibitors.In VitroM1002 (10 μM: 24 h) enhances the expression of HIF-2 target

LEO 39652 is a dual-soft PDE4 inhibitor with IC 50 s of 1.2 nM, 1.2 nM, 3.0 nM and 3.8 nM for PDE4A , PDE4B , PDE4C and PDE4D , respectively. LEO 39652 also inhibits TNF-α with an IC 50 value of 6.0 nM. LEO 39652 is used for topical research of

BDP 581/591 alkyne is a derivative of BDP which can be used in fluorescence polarization assays. The addition of the azide allows for it to be used in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN.

BDP 581/591 alkyne is a derivative of BDP which can be used in fluorescence polarization assays. The addition of the azide allows for it to be used in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN.

BDP 581/591 alkyne is a derivative of BDP which can be used in fluorescence polarization assays. The addition of the azide allows for it to be used in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN.

AER-271, a phosphonate proagent derivative of AER-270, is an aquaporin-4 ( AQP4 ) inhibitor for the research of acute ischemic strokeIn VivoAER-271 is converted in vivo to AER-270 by endogenous phosphatases. AER-271 blocks acute cerebral edema and

AG-270 is an allosteric, noncompetitive, first-in-class, reversible and orally active MAT2A inhibitor, with an IC 50 of 14 nMIn VitroAG-270 demonstrates potent reduction in levels of intracellular SAM , as well as MTAP-–selective antiproliferative

AER-271 is an inhibitor of aquaporin-4.In Vivo：Treatment with AER-271 ameliorated early cerebral edema measured at 3 h after CA vs vehicle treated rats. This treatment also attenuated early NDS. In contrast to rats treated with vehicle after CA,

AER-271 is an inhibitor of aquaporin-4.In Vivo：Treatment with AER-271 ameliorated early cerebral edema measured at 3 h after CA vs vehicle treated rats. This treatment also attenuated early NDS. In contrast to rats treated with vehicle after CA,

AER-271 is an inhibitor of aquaporin-4.In Vivo：Treatment with AER-271 ameliorated early cerebral edema measured at 3 h after CA vs vehicle treated rats. This treatment also attenuated early NDS. In contrast to rats treated with vehicle after CA,