AER-271 is an inhibitor of aquaporin-4.In Vivo:Treatment with AER-271 ameliorated early cerebral edema measured at 3 h after CA vs vehicle treated rats. This treatment also attenuated early NDS. In contrast to rats treated with vehicle after CA, rats treated with AER-271 did not develop significant neuronal death or neuroinflammation as compared to sham.IC50& Target:Aquaporin-4 (AQP4).
Specifications and Purity: ≥98%
Molecular Formula: C15H9ClF6NO5P
Molecular Weight: 463.65
PubChem CID: 10412080
Isomeric SMILES: C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)OP(=O)(O)O
- UPC:
- 41113402
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A649710-25mg
- CAS:
- 634913-39-6
- Product Size:
- 25mg
akash.verma@cenmed.com
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