Sodium/H2 exchanger-1 (NHE-1) inhibitor; inhibited NHE-1-mediated rabbit platelet swelling; in anesthetized rats, reduced infarct size from 67% (control) to 43% (at 0.1 mg/kg) and 24% (at 1.0 mg/kg); reduced number of ventricular premature beats from 530 to 266 (at 0.1 mg/kg) and 115 (at 1.0 mg/kg); reduced ventricular fibrillation incidence from 17 to 8 (0.1 mg/kg) and 0 (1.0 mg/kg); implications for research and treatment of myocardial ischemic diseases.
Specifications and Purity: ≥98%
Molecular Formula: C13H12FN3O2
Molecular Weight: 261.25
PubChem CID: 11368995
Isomeric SMILES: CC1=C(C=C(C=C1)F)C2=CC=C(O2)C(=O)N=C(N)N
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/K336935-SCI_a1c451effd483389cc5c50d8e9551b9e.pdf
- UPC:
- 41116106
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- K336935-5mg
- CAS:
- 852146-73-7
- Product Size:
- 5mg
- Hazard Statement Codes:
- H335:H319:H315:H302
- Precautionary Statement Codes:
- P501:P403+P233:P405:P362+P364:P305+P351+P338:P304+P340:P302+P352:P301+P312:P330:P280:P271:P270:P264:P261
akash.verma@cenmed.com
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