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fty720 (r)-phosphate

FTY720 (R)-Phosphate (C007B-166498)

Catalog No.
C007B-166498
Manufacturer No.
F334674-500μg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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FTY720 (R)-Phosphate, FTY720 is a novel immune modulator that inhibits lymphocyte emigration from lymphoid organs, which prolongs allograft transplant survival in numerous models. Sphingosine kinases phosphorylate FTYS20 in vivo so that FTYS20 acts

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FTY720 (R)-Phosphate, FTY720 is a novel immune modulator that inhibits lymphocyte emigration from lymphoid organs, which prolongs allograft transplant survival in numerous models. Sphingosine kinases phosphorylate FTYS20 in vivo so that FTYS20 acts as a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors . FTY720 (R)-phosphate is one stereoisomer of FTY720-phosphate, but it is evidently not formed in vivo. FTY720 (S)-phosphate exhibits K|i|values of 2.1, 5.9, 23, and 2.2 nM for S1P1,3,4,5, respectively, while the R isomer binds with 5-130-fold lower affinity.

Specifications and Purity: ≥98%

Molecular Formula: C19H34NO5P

Molecular Weight: 387.5

PubChem CID: 9908268

Isomeric SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(COP(=O)(O)O)N

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/F334674-SCI_14641856e7cf25bcfeca8abf1cad6b5d.pdf

UPC:
12141909
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
F334674-500μg
CAS:
402616-23-3
Product Size:
500μg
Precautionary Statement Codes:
P264

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