FTY720 Phosphate is a derivative of ISP-1 (myriocin) that is a fungal metabolite of the Chinese herb|Iscaria sinclarii|and a structural analog of sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. It is phosphorylated by sphingosine kinase to the physiologically active phosphoric acid ester. FTY720 phosphate acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (EDG-1, EDG-3, EDG-4, and EDG-5), with IC|50|values of 0.2-6 nM.
Specifications and Purity: ≥95%
Molecular Formula: C19H34NO5P
Molecular Weight: 387.45
PubChem CID: 9908268
Isomeric SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(COP(=O)(O)O)N
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/F333868-SCI_797187b4e5aa41a6197c3984199ca6c5.pdf
- UPC:
- 12131805
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- F333868-1mg
- CAS:
- 402615-91-2
- Product Size:
- 1mg
- Precautionary Statement Codes:
- P264
akash.verma@cenmed.com
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