General description
The Mtt group can be removed from the side-chain of histidine by treatment with dilute TFA [1].
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] K. Barlos, et al. (1991) Tetrahedron Lett., 32, 475.
Linkage
Replaces: 04-12-1108
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 94.0 %
Water (K. F.): ≤ 5.0 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Molecular Weight: 633.73. Empirical Formula: C41H35N3O4. Quality Level: 200. product line: Novabiochem®. . Assay: ≥. 94.0% (acidimetric), ≥. 98% (TLC), ≥. 98.0% (HPLC). form: powder. reaction suitability: reaction type: Fmoc solid-phase peptide synthesis. manufacturer/tradename: Novabiochem®. . application(s): peptide synthesis. functional group: Fmoc. storage temp.: 15-25°C. InChI: 1S/C41H35N3O4/c1-28-20-22-31(23-21-28)41(29-12-4-2-5-13-29,30-14-6-3-7-15-30)44-25-32(42-27-44)24-38(39(45)46)43-40(47)48-26-37-35-18-10-8-16-33(35)34-17-9-11-19-36(34)37/h2-23,25,27,37-38H,24,26H2,1H3,(H,43,47)(H,45,46)/t38-/m0/s1. InChI key: MNOCIIYDYLYWEU-LHEWISCISA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 42202301
- Condition:
- New
- HazmatClass:
- No
- MPN:
- 8522110005
- CAS:
- 133367-34-7
akash.verma@cenmed.com
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