E-7386 is an orally active CBP/beta-catenin modulator.In VivoE-7386 is an orally active CBP/beta-catenin modulator which can induce T cells infiltration into tumor and enhance antitumor activity of anti-PD-1 mAb in Wnt1 tumor syngeneic mice model. E-7386 shows significant antitumor activity in Wnt1 model. Infiltration of T cells is limited in vehicle control group, but T cell infiltration into tumors is clearly observed in E-7386 treatment group . MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:CBP/beta-catenin.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C39H48FN9O4
Molecular Weight: 725.85
- UPC:
- 41101808
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- E656399-1ml
- CAS:
- 1799824-08-0
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





