E-7386 is an orally active CBP/beta-catenin modulator.In VivoE-7386 is an orally active CBP/beta-catenin modulator which can induce T cells infiltration into tumor and enhance antitumor activity of anti-PD-1 mAb in Wnt1 tumor syngeneic mice model. E-7386 shows significant antitumor activity in Wnt1 model. Infiltration of T cells is limited in vehicle control group, but T cell infiltration into tumors is clearly observed in E-7386 treatment group . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:CBP/beta-catenin.
Specifications and Purity: ≥99%
Molecular Formula: C39H48FN9O4
Molecular Weight: 725.85
PubChem CID: 91810345
Isomeric SMILES: CCN1CCN(CC1)C2CN(C2)C3=CC=CC(=N3)CN4C[C@H]5N([C@H](C4=O)CC6=C(C=C(C=C6)O)F)C(=O)CN(N5C(=O)NCC7=CC=CC=C7)CC=C
- UPC:
- 41101808
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- E650751-10mg
- CAS:
- 1799824-08-0
- Product Size:
- 10mg
akash.verma@cenmed.com
(732) 447-1115





