DLK-IN-1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12) , with a K i of 3 nM. DLK-IN-1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK-IN-1 has activity in a model of Alzheimer’s Disease.IC50& Target:Ki: 3 nM (DLK).
Specifications and Purity: 10mM in DMSO
Molecular Formula: C20H24F3N5O2
Molecular Weight: 423.43
- UPC:
- 41104815
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D656216-1ml
- CAS:
- 1620574-24-4
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





