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DCA DEBLOCK (TOLUENE) (C005B-225393)

Catalog No.
C005B-225393
Manufacturer No.
L023050-180L
Manufacturer Name
Sigma-Aldrich
Quantity
180
Unit of Measure
LI

Deblock solution containing dichloroacetic acid (DCA) in toluene removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the

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General description

Deblock solution containing dichloroacetic acid (DCA) in toluene removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. This solution contains toluene / Dichloroactic Acid (97/3 v/v).

Application

DCA Deblock solution facilitates removal of the DMT that allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

Preparation Note

Toluene / Dichloroacetic acid 97/3 (v/v)

Legal Information

OligoPilot is a registered trademark of Cytiva

ÄKTA is a registered trademark of Cytiva

description: with Toluene. Quality Level: 200. type: for DNA synthesis, for DNA synthesis. storage condition: dry at room temperature. concentration: 42.2-51.6 . g/L (DCA content, titration). impurities: ≤. 200 . ppm water content (Karl Fischer). color: clear. compatibility: configured for (ÄKTA®. and OligoPilot®. ). Pictograms: GHS02,GHS05,GHS07,GHS08,GHS09. Signal Word: Danger. Hazard Statements: H225 - H304 - H315 - H318 - H336 - H351 - H360FD - H373 - H410. Precautionary Statements: P210 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P331. Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 - STOT SE 3. Target Organs: Central nervous system. Storage Class Code: 3 - Flammable liquids. WGK: WGK 3. Flash Point(F): 39.2 °F. Flash Point(C): 4.0 °C.
UPC:
41105903
Condition:
New
HazmatClass:
Yes
MPN:
L023050-180L

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