General description
Deblock solution containing dichloroacetic acid (DCA) in toluene removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. This solution contains toluene / Dichloroactic Acid (97/3 v/v).
Application
DCA Deblock solution facilitates removal of the DMT that allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.
Preparation Note
Toluene / Dichloroacetic acid 97/3 (v/v)
Legal Information
OligoPilot is a registered trademark of Cytiva
ÄKTA is a registered trademark of Cytiva
description: with Toluene. Quality Level: 200. type: for DNA synthesis, for DNA synthesis. storage condition: dry at room temperature. concentration: 42.2-51.6 . g/L (DCA content, titration). impurities: ≤. 200 . ppm water content (Karl Fischer). color: clear. compatibility: configured for (ÄKTA®. and OligoPilot®. ). Pictograms: GHS02,GHS05,GHS07,GHS08,GHS09. Signal Word: Danger. Hazard Statements: H225 - H304 - H315 - H318 - H336 - H351 - H360FD - H373 - H410. Precautionary Statements: P210 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P331. Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 - STOT SE 3. Target Organs: Central nervous system. Storage Class Code: 3 - Flammable liquids. WGK: WGK 3. Flash Point(F): 39.2 °F. Flash Point(C): 4.0 °C.- UPC:
- 41105903
- Condition:
- New
- HazmatClass:
- Yes
- MPN:
- L023050-180L
akash.verma@cenmed.com
(732) 447-1115





