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cgp 74514a

CGP 74514A (C007B-100915)

Catalog No.
C007B-100915
Manufacturer No.
C380688-5mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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CGP 74514A is a cell permeable, potent, and selective inhibitor of CDK1/cyclin B (IC|50|= 25 nM). CGP 74514A is reported to affect the activities of other kinases only at much higher concentrations, such as PKCα (IC|50|= 6.1 μM), PKA (IC|50|= 125

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CGP 74514A is a cell permeable, potent, and selective inhibitor of CDK1/cyclin B (IC|50|= 25 nM). CGP 74514A is reported to affect the activities of other kinases only at much higher concentrations, such as PKCα (IC|50|= 6.1 μM), PKA (IC|50|= 125 μM) and EGFR (IC|50|> 10 μM). CGP 74514A induces mitochondrial damage and apoptosis in several human leukemia cell lines (>3μM).CGP 74514Ais An inhibitor of CDK1/cyclin B, PKCα, PKA, and EGFR.

Specifications and Purity: ≥95%

Molecular Formula: C19H24ClN7

Molecular Weight: 385.89

PubChem CID: 2794188

Isomeric SMILES: CCN1C=NC2=C(N=C(N=C21)N[C@@H]3CCCC[C@@H]3N)NC4=CC(=CC=C4)Cl

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/C380688-SCI_6793a89d067109dd3801387b44a4e3d1.pdf

UPC:
12171604
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
C380688-5mg
Product Size:
5mg
Hazard Statement Codes:
H335:H319:H315
Precautionary Statement Codes:
P280:P271:P264:P261

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