CGP 74514A is a cell permeable, potent, and selective inhibitor of CDK1/cyclin B (IC|50|= 25 nM). CGP 74514A is reported to affect the activities of other kinases only at much higher concentrations, such as PKCα (IC|50|= 6.1 μM), PKA (IC|50|= 125 μM) and EGFR (IC|50|> 10 μM). CGP 74514A induces mitochondrial damage and apoptosis in several human leukemia cell lines (>3μM).CGP 74514Ais An inhibitor of CDK1/cyclin B, PKCα, PKA, and EGFR
Specifictaions: Moligand™, ≥95%
MDL Number: C19H24ClN7
Molecular Formula: 385.89
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/C380688-SCI_6793a89d067109dd3801387b44a4e3d1.pdf
- UPC:
- 12171604
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C380688-1mg
- CAS:
- 190653-73-7
- Product Size:
- 1mg
akash.verma@cenmed.com
(732) 447-1115





