BORANE-METHYL SULFIDE COMPLEX 2.0M SOLUTION IN TETRAHYDROFURAN (C005B-015172)

General description

Borane dimethyl sulfide complex (BMS) acts as a highly efficient and selective reducing agent in the presence of catalytic sodium tetrahydroborate for α-hydroxy esters. Asymmetric borane reduction of a variety of prochiral ketones with BMS using spiroborate esters as catalyst has been reported.

Application

Borane dimethyl sulfide complex (BMS) solution may be used in the following studies:

• One-pot conversion of alkynes into 1,2-diols.
• Preparation of iminopentitols.
• Reduction of representative organic functional groups, such as esters, nitriles and amides.
• Used along with a dendrimeric supported L-pyrrolidinol in the asymmetric reduction of indanones and tetralones.
• Asymmetric reduction of ferrocenyl-1,3-diketones to chiral 1,3-diols.
• Highly enantioselective reduction of ketones catalyzed by C₃-symmetric tripodal hydroxyamides.

Reactant used as a regioselective reducing agent

Reactant involved in:

• Hydroboration / oxidation

Synthesis of cage compounds

Molecular Weight: 75.97. Empirical Formula: C₂H₉BS. linearFormula: (CH₃)₂S · BH₃. form: liquid. Quality Level: 200. reaction suitability: reagent type: reductant. concentration: 2.0 . M in THF. density: 0.855 . g/mL . at 25 . °C. storage temp.: 2-8°C. SMILES string: B.CSC. InChI: 1S/C2H6S.BH3/c1-3-2. /h1-2H3. 1H3. InChI key: RMHDLBZYPISZOI-UHFFFAOYSA-N. Pictograms: GHS02,GHS05,GHS07,GHS08. Signal Word: Danger. Hazard Statements: H225 - H260 - H302 + H312 - H318 - H335 - H336 - H351 - H360FD. Precautionary Statements: P210 - P231 + P232 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P308 + P313. Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Water-react 1. Supp Hazards: EUH019. Storage Class Code: 4.3 - Hazardous materials, which set free flammable gases upon contact with water. WGK: WGK 1. Flash Point(F): 1.4 °F - closed cup. Flash Point(C): -17 °C - closed cup. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter.