?-ESTRADIOL 3-BENZOATE >= 97% (C005B-045120)

Application

β-Estradiol 3-benzoate has been used:to mimic estradiol in rat during the oestrous cycle in rats. It has also been used along with progesterone for the induction of sexual receptivity in female rat.

Used in a study of general steroid metabolism and clearing, as groundwork for anabolic steroid screening in athletes.

Biochem/physiol Actions

β-Estradiol 3-benzoate is a synthetic estrogen. It favors breast cancer progression. It is an endocrine disrupting chemicals. It interacts with endocrine system and cause harmful effect on reproduction in animals and humans. It binds to estrogen receptors and favors tumor metastatis in breast, prostate and bone cells.

Molecular Weight: 376.49. Empirical Formula: C₂₅H₂₈O₃. Quality Level: 200. Assay: ≥. 97%. mp: 191-198 . °C (lit.). SMILES string: [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OC(: O)c5ccccc5)ccc24. InChI: 1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1. InChI key: UYIFTLBWAOGQBI-BZDYCCQFSA-N. Pictograms: GHS08. Signal Word: Danger. Hazard Statements: H351 - H360FD. Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501. Hazard Classifications: Carc. 2 - Repr. 1B. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Personal Protective Equipment: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges.