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acivicin

Acivicin

Catalog No.
C007B-006590
Manufacturer No.
A134970-10mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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An inhibitor of GGT used for solid tumor researchAcivicin is an antineoplastic antibiotic believed to act by interfering with glutamine metabolism which has been administered for research in a variety of solid tumors. Bone marrow depression and

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An inhibitor of GGT used for solid tumor researchAcivicin is an antineoplastic antibiotic believed to act by interfering with glutamine metabolism which has been administered for research in a variety of solid tumors. Bone marrow depression and central neurotoxicity has been observed to suggest that it may be dose-limiting. Acivicin is an irreversible inhibitor of GGT (γ-glutamyl transpeptidase) ID50 = 0.54 mM. Additionally, it inhibits the enzymatic conversion of leukotriene C4 to leukotriene D4 and the bioactivation and release of nitric oxide from GSNO6. Also, the product displays anti tumor and anti-metastatic activity and blocks H. Pylori GGT-induced T-cell inhibition.

Specifications and Purity: ≥97%

MDL Number: MFCD00866432

Molecular Formula: C5H7ClN2O3

Molecular Weight: 178.57

PubChem CID: 294641

Isomeric SMILES: C1[C@H](ON=C1Cl)[C@@H](C(=O)O)N

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/A134970-SCI_905582e037d368c6553d3867ae083e1c.pdf

UPC:
42183019
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
A134970-10mg
CAS:
42228-92-2
Product Size:
10mg
Hazard Statement Codes:
H302
Precautionary Statement Codes:
P270:P264

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