An inhibitor of GGT used for solid tumor researchAcivicin is an antineoplastic antibiotic believed to act by interfering with glutamine metabolism which has been administered for research in a variety of solid tumors. Bone marrow depression and central neurotoxicity has been observed to suggest that it may be dose-limiting. Acivicin is an irreversible inhibitor of GGT (γ-glutamyl transpeptidase) ID50 = 0.54 mM. Additionally, it inhibits the enzymatic conversion of leukotriene C4 to leukotriene D4 and the bioactivation and release of nitric oxide from GSNO6. Also, the product displays anti tumor and anti-metastatic activity and blocks H. Pylori GGT-induced T-cell inhibition.
Specifictaions: Moligand™, ≥97%
Specification: MFCD00866432
MDL Number: C5H7ClN2O3
Molecular Formula: 178.57
PubChem CID: 294641
Isomeric SMILES: C1[C@H](ON=C1Cl)[C@@H](C(=O)O)N
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A134970-SCI_905582e037d368c6553d3867ae083e1c.pdf
- UPC:
- 51152010
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A134970-2.5mg
- CAS:
- 42228-92-2
- Product Size:
- 2.5mg
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